Cookie Consent: We use cookies to give you the best online experience, for analytics, performance, and to tailor the experience towards your interests.

Skip to content
Pic of The Model Health Show

This Breakthrough in Alzheimer’s Research Can Save Millions of Lives - With Dr. David Perlmutter

August 3, 2026
0 comments

The Model Health Show

Description

Alzheimer’s disease has grown to become the most common form of dementia, and as of now, there is no cure for this devastating neurodegenerative disease. But new science shows that your brain’s immune cells play an essential role in how your brain ages. Today, you’re going to learn this latest science and how to put it into action.  Today’s guest, Dr. David Perlmutter is a board-certified neurologist and six-time New York Times bestselling author. His new book, Brain Defenders, dives into the groundbreaking discovery that immune cells in the brain are the key to brain health and longevity. On this episode, you’re going to learn about this emerging science and what you can do to protect your brain now and as you age.  In this interview, you’re going to learn about the fascinating science of immunometabolism, what microglial cells are, and the specific lifestyle habits that can shape the future of your brain. We’re going to talk about specific foods and exercises that can dictate the health of your brain’s immune cells, and proven strategies to protect your brain from degradation. Enjoy!  In this episode you’ll discover: The one fundamental mechanism that connects all neurodegenerative diseases. (2:26) What the latest science says about the efficacy of Alzheimer’s medications. (3:41) The essential function of microglial cells. (6:51)  What immunometabolism is. (8:41)  How having type 2 diabetes can increase your risk of Alzheimer’s disease. (11:23) What GLP-1 drugs teach us about the link between the brain and metabolism. (12:12) How exercise helps defend the brain from degeneration. (29:12) The connection between myokines and metabolism. (29:54) Why flexibility and balance training are important for longevity. (36:57) The truth about fish oil supplements for brain health. (38:14) What to eat to defend your brain. (42:21) How eating ultraprocessed foods increases your risk of brain diseases. (45:38) Why stress impacts your brain health. (57:10) The simplest way to measure your health and activity levels. (1:08:23) Items mentioned in this episode include: DrinkLMNT.com/model - Get a truly meaningful dose of electrolytes in a science-backed ratio. Free sample pack with any order. Organifi.com/Model - Organifi makes nutrition easy and delicious for everyone. Take 20% off your order with the code MODEL. Brain Defenders by Dr. David Perlmutter - Preorder your copy of Dr. Perlmutter’s new book today!  Grain Brain by Dr. David Perlmutter - Read about how your diet affects your brain health!  You’ve Been Pooping All Wrong by Dr. Trisha Pasricha - Learn about gut health and how to poop better!  Connect with Dr. David Perlmutter Website / Podcast / Facebook / Instagram  Be sure you are subscribed to this podcast to automatically receive your episodes:  Apple Podcasts Spotify Soundcloud Pandora YouTube  This episode of The Model Health Show is brought to you by LMNT and Organifi.  Most people are underhydrated—and it’s costing you energy, focus, and performance. LMNT delivers a science-backed electrolyte ratio with no sugar, no junk—just what your body actually needs. Get a free sample pack with any order at drinklmnt.com/model.  Make nutrition effortless—and actually enjoyable. Organifi’s delicious, superfood blends help you boost energy, reduce stress, and feel your best every day. Get 20% off with code MODEL at organifi.com/model.